| Bus From Karaikudi To | Departure Time |
| MPTC (Chennai) | 8:15 AM, 8:45 AM |
| TNSTC (Chennai) | 8:00 PM |
| Bangalore | 7:30 PM |
| Coimbatore | 8:30 PM |
| Chennai | 7:45 PM |
| Chennai | 8:15 PM |
| Chennai | 8:30 PM |
| Chennai | 8:45 PM |
| Puduvayal - Chennai | 7:00 PM |
| Madurai (Matuthavani Bus Stand) - Tiruppathi | 6:30 PM, 9:30 PM |
| Trichy (Central Bus Stand) - Tiruppathi | 8:00 AM, 9:00 AM, 7:00 PM, 9:00 PM,10:00 PM |
| Chennai - 133UD(ultra Deluxe) | 08:30, 09:30, 19:00, 20:00, 20:45, 21:00, 21:30 |
| Chennai - 165AS(A/c Sleeper) | 21:20 |
| Tirupati - 969 | 18:00 |
| Bangalore - 857 | 19:30, 20:30 |
| Coimbatore - 603 | 21:30 |
